FOCUS Centers are setup in cities/regions to provide a hands-on outreach to the poor, needy and suffering in an area. The centers are established in a neighborhood or community with great need and are run by a local director employed by FOCUS North America and staffed with volunteers from local Orthodox churches and others. They are initially centered around a feeding program but also have several life-recovery ministries.

Services at FOCUS Centers are based upon the need of an area. The services they provide may include the following: community meals, food pantry, mobile hospitality outreach, companionship ministries, counseling and case management, shelter referrals, occupational training, clothing closets and other vital life recovery services.